Cargando…
Thermal difference spectra: a specific signature for nucleic acid structures
We show that nucleic acid structures may be conveniently and inexpensively characterized by their UV thermal difference spectra. A thermal difference spectrum (TDS) is obtained for a nucleic acid by simply recording the ultraviolet absorbance spectra of the unfolded and folded states at temperatures...
Autores principales: | Mergny, Jean-Louis, Li, Jing, Lacroix, Laurent, Amrane, Samir, Chaires, Jonathan B. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201377/ https://www.ncbi.nlm.nih.gov/pubmed/16157860 http://dx.doi.org/10.1093/nar/gni134 |
Ejemplares similares
-
Shape matters: size-exclusion HPLC for the study of nucleic acid structural polymorphism
por: Largy, Eric, et al.
Publicado: (2014) -
Sequence- and structural-selective nucleic acid binding revealed by the melting of mixtures
por: Shi, Xiaochun, et al.
Publicado: (2006) -
Fluorescence-based duplex–quadruplex competition test to screen for telomerase RNA quadruplex ligands
por: Lacroix, Laurent, et al.
Publicado: (2011) -
A rapid fluorescent indicator displacement assay and principal component/cluster data analysis for determination of ligand–nucleic acid structural selectivity
por: del Villar-Guerra, Rafael, et al.
Publicado: (2018) -
Revision of the nonequilibrium thermal dissociation and stringent washing approaches for identification of mixed nucleic acid targets by microarrays
por: Pozhitkov, Alex E., et al.
Publicado: (2007)