Improved prediction of critical residues for protein function based on network and phylogenetic analyses

BACKGROUND: Phylogenetic approaches are commonly used to predict which amino acid residues are critical to the function of a given protein. However, such approaches display inherent limitations, such as the requirement for identification of multiple homologues of the protein under consideration. The...

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Detalles Bibliográficos
Autores principales: Thibert, Boris, Bredesen, Dale E, del Rio, Gabriel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208857/
https://www.ncbi.nlm.nih.gov/pubmed/16124876
http://dx.doi.org/10.1186/1471-2105-6-213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208857/
https://www.ncbi.nlm.nih.gov/pubmed/16124876
http://dx.doi.org/10.1186/1471-2105-6-213

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