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Improved prediction of critical residues for protein function based on network and phylogenetic analyses
BACKGROUND: Phylogenetic approaches are commonly used to predict which amino acid residues are critical to the function of a given protein. However, such approaches display inherent limitations, such as the requirement for identification of multiple homologues of the protein under consideration. The...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208857/ https://www.ncbi.nlm.nih.gov/pubmed/16124876 http://dx.doi.org/10.1186/1471-2105-6-213 |