Cargando…
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming
BACKGROUND: Mouse preimplantation development is characterized by both active and passive genomic demethylation. A short isoform of the prevalent maintenance DNA methyltransferase (Dnmt1S) is found in the cytoplasm of preimplantation embryos and transiently enters the nucleus only at the 8-cell stag...
Autores principales: | , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208874/ https://www.ncbi.nlm.nih.gov/pubmed/16120212 http://dx.doi.org/10.1186/1471-213X-5-18 |