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Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming

BACKGROUND: Mouse preimplantation development is characterized by both active and passive genomic demethylation. A short isoform of the prevalent maintenance DNA methyltransferase (Dnmt1S) is found in the cytoplasm of preimplantation embryos and transiently enters the nucleus only at the 8-cell stag...

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Detalles Bibliográficos
Autores principales:	Grohmann, Maik, Spada, Fabio, Schermelleh, Lothar, Alenina, Natalia, Bader, Michael, Cardoso, M Cristina, Leonhardt, Heinrich
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208874/ https://www.ncbi.nlm.nih.gov/pubmed/16120212 http://dx.doi.org/10.1186/1471-213X-5-18

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