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Analysis of blood coagulation in mice: pre-analytical conditions and evaluation of a home-made assay for thrombin-antithrombin complexes

BACKGROUND: The use of mouse models for the study of thrombotic disorders has gained increasing importance. Methods for measurement of coagulation activation in mice are, however, scarce. The primary aim of this study was to develop a specific mouse thrombin-antithrombin (TAT) ELISA for measurement...

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Detalles Bibliográficos
Autores principales: Sommeijer, Dirkje W, van Oerle, René, Reitsma, Pieter H, Timmerman, Janneke J, Meijers, Joost CM, Spronk, Henri MH, ten Cate, Hugo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1215525/
https://www.ncbi.nlm.nih.gov/pubmed/16115315
http://dx.doi.org/10.1186/1477-9560-3-12