Determination of Cytochrome P450 2D6 (CYP2D6) Gene Copy Number by Real-Time Quantitative PCR

Gene dosage by real-time quantitative PCR has proved to be accurate for measuring gene copy number. The aim of this study was to apply this approach to the CYP2D6 gene to allow for rapid identification of poor and ultrarapid metabolizers (0, 1, or more than 2 gene copy number). Using the 2(−ΔΔCt) ca...

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Detalles Bibliográficos
Autores principales: Bodin, Laurent, Beaune, Philippe H., Loriot, Marie-Anne
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224698/
https://www.ncbi.nlm.nih.gov/pubmed/16192683
http://dx.doi.org/10.1155/JBB.2005.248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224698/
https://www.ncbi.nlm.nih.gov/pubmed/16192683
http://dx.doi.org/10.1155/JBB.2005.248

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