Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor

Non-homologous end joining (NHEJ) and homologous recombination (HR) are pathways that repair DNA double-strand breaks (DSBs). In Saccharomyces cerevisiae, the repair of these breaks is influenced by histone acetylation. Therefore, we tested mammalian cells deleted for NHEJ (Ku80 or DNA Ligase IV) or...

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Detalles Bibliográficos
Autores principales: Yaneva, Mariana, Li, Han, Marple, Teresa, Hasty, Paul
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226312/
https://www.ncbi.nlm.nih.gov/pubmed/16177181
http://dx.doi.org/10.1093/nar/gki821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226312/
https://www.ncbi.nlm.nih.gov/pubmed/16177181
http://dx.doi.org/10.1093/nar/gki821

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