Cargando…
Mortality following Campylobacter infection: a registry-based linkage study
BACKGROUND: Campylobacteriosis is one of the most commonly identified causes of bacterial diarrheal disease and a common cause of gastroenteritis in travellers from developed nations. Despite the widespread occurrence, there is little information on Campylobacter mortality. METHODS: Mortality among...
Autores principales: | , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236927/ https://www.ncbi.nlm.nih.gov/pubmed/16162289 http://dx.doi.org/10.1186/1471-2334-5-70 |
_version_ | 1782125011075596288 |
---|---|
author | Ternhag, Anders Törner, Anna Svensson, Åke Giesecke, Johan Ekdahl, Karl |
author_facet | Ternhag, Anders Törner, Anna Svensson, Åke Giesecke, Johan Ekdahl, Karl |
author_sort | Ternhag, Anders |
collection | PubMed |
description | BACKGROUND: Campylobacteriosis is one of the most commonly identified causes of bacterial diarrheal disease and a common cause of gastroenteritis in travellers from developed nations. Despite the widespread occurrence, there is little information on Campylobacter mortality. METHODS: Mortality among a cohort of Campylobacter cases were compared with the general population 0–1, 1–3, 3–12 and more than 12 month after the onset of the illness. The cases were sub-grouped according to if they had been infected domestically or abroad. RESULTS: The standardized mortality ratio for cases infected domestically was 2.9 (95% CI: 1.9–4.0) within the first month following the illness. The risk then gradually diminished and approached 1.0 after one year or more have passed since the illness. This initial excess risk was not attributable to any particular age group (such as the oldest). In contrast, for those infected abroad, a lower standardized mortality ratio 0.3 (95% CI: 0.04–0.8) was shown for the first month after diagnosis compared to what would be expected in the general population. CONCLUSION: Infection with Campylobacter is associated with an increased short-term risk of death among those who were infected domestically. On the contrary, for those infected abroad a lower than expected risk of death was evident. We suggest that the explanation behind this is a "healthy traveler effect" among imported cases, and effects of a more frail than average population among domestic cases. |
format | Text |
id | pubmed-1236927 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-12369272005-09-29 Mortality following Campylobacter infection: a registry-based linkage study Ternhag, Anders Törner, Anna Svensson, Åke Giesecke, Johan Ekdahl, Karl BMC Infect Dis Research Article BACKGROUND: Campylobacteriosis is one of the most commonly identified causes of bacterial diarrheal disease and a common cause of gastroenteritis in travellers from developed nations. Despite the widespread occurrence, there is little information on Campylobacter mortality. METHODS: Mortality among a cohort of Campylobacter cases were compared with the general population 0–1, 1–3, 3–12 and more than 12 month after the onset of the illness. The cases were sub-grouped according to if they had been infected domestically or abroad. RESULTS: The standardized mortality ratio for cases infected domestically was 2.9 (95% CI: 1.9–4.0) within the first month following the illness. The risk then gradually diminished and approached 1.0 after one year or more have passed since the illness. This initial excess risk was not attributable to any particular age group (such as the oldest). In contrast, for those infected abroad, a lower standardized mortality ratio 0.3 (95% CI: 0.04–0.8) was shown for the first month after diagnosis compared to what would be expected in the general population. CONCLUSION: Infection with Campylobacter is associated with an increased short-term risk of death among those who were infected domestically. On the contrary, for those infected abroad a lower than expected risk of death was evident. We suggest that the explanation behind this is a "healthy traveler effect" among imported cases, and effects of a more frail than average population among domestic cases. BioMed Central 2005-09-14 /pmc/articles/PMC1236927/ /pubmed/16162289 http://dx.doi.org/10.1186/1471-2334-5-70 Text en Copyright © 2005 Ternhag et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Ternhag, Anders Törner, Anna Svensson, Åke Giesecke, Johan Ekdahl, Karl Mortality following Campylobacter infection: a registry-based linkage study |
title | Mortality following Campylobacter infection: a registry-based linkage study |
title_full | Mortality following Campylobacter infection: a registry-based linkage study |
title_fullStr | Mortality following Campylobacter infection: a registry-based linkage study |
title_full_unstemmed | Mortality following Campylobacter infection: a registry-based linkage study |
title_short | Mortality following Campylobacter infection: a registry-based linkage study |
title_sort | mortality following campylobacter infection: a registry-based linkage study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236927/ https://www.ncbi.nlm.nih.gov/pubmed/16162289 http://dx.doi.org/10.1186/1471-2334-5-70 |
work_keys_str_mv | AT ternhaganders mortalityfollowingcampylobacterinfectionaregistrybasedlinkagestudy AT torneranna mortalityfollowingcampylobacterinfectionaregistrybasedlinkagestudy AT svenssonake mortalityfollowingcampylobacterinfectionaregistrybasedlinkagestudy AT gieseckejohan mortalityfollowingcampylobacterinfectionaregistrybasedlinkagestudy AT ekdahlkarl mortalityfollowingcampylobacterinfectionaregistrybasedlinkagestudy |