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Characterization of the bisintercalative DNA binding mode of a bifunctional platinum–acridine agent
The DNA interactions of PT-BIS(ACRAMTU) ([Pt(en)(ACRAMTU)(2)](NO(3))(4); ACRAMTU = 1-[2-(acridin-9-ylamino)ethyl]-1,3-dimethylthiourea, en = ethylenediamine), a bifunctional platinum–acridine conjugate, have been studied in native and synthetic double-stranded DNAs and model duplexes using various b...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236979/ https://www.ncbi.nlm.nih.gov/pubmed/16192574 http://dx.doi.org/10.1093/nar/gki869 |