Ancient Origin and Gene Mosaicism of the Progenitor of Mycobacterium tuberculosis

The highly successful human pathogen Mycobacterium tuberculosis has an extremely low level of genetic variation, which suggests that the entire population resulted from clonal expansion following an evolutionary bottleneck around 35,000 y ago. Here, we show that this population constitutes just the...

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Detalles Bibliográficos
Autores principales: Gutierrez, M. Cristina, Brisse, Sylvain, Brosch, Roland, Fabre, Michel, Omaïs, Bahia, Marmiesse, Magali, Supply, Philip, Vincent, Veronique
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238740/
https://www.ncbi.nlm.nih.gov/pubmed/16201017
http://dx.doi.org/10.1371/journal.ppat.0010005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238740/
https://www.ncbi.nlm.nih.gov/pubmed/16201017
http://dx.doi.org/10.1371/journal.ppat.0010005

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