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Ancient Origin and Gene Mosaicism of the Progenitor of Mycobacterium tuberculosis
The highly successful human pathogen Mycobacterium tuberculosis has an extremely low level of genetic variation, which suggests that the entire population resulted from clonal expansion following an evolutionary bottleneck around 35,000 y ago. Here, we show that this population constitutes just the...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238740/ https://www.ncbi.nlm.nih.gov/pubmed/16201017 http://dx.doi.org/10.1371/journal.ppat.0010005 |