A biologically based model of growth and senescence of Syrian hamster embryo (SHE) cells after exposure to arsenic.

We modified the two-stage Moolgavkar-Venzon-Knudson (MVK) model for use with Syrian hamster embryo (SHE) cell neoplastic progression. Five phenotypic stages are proposed in this model: Normal cells can either become senescent or mutate into immortal cells followed by anchorage-independent growth and...

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Detalles Bibliográficos
Autores principales: Liao, K H, Gustafson, D L, Fox, M H, Chubb, L S, Reardon, K F, Yang, R S
Formato: Texto
Lenguaje:English
Publicado: 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240502/
https://www.ncbi.nlm.nih.gov/pubmed/11748027

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