The value of plants used in traditional medicine for drug discovery.

In this review we describe and discuss several approaches to selecting higher plants as candidates for drug development with the greatest possibility of success. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discove...

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Detalles Bibliográficos
Autores principales: Fabricant, D S, Farnsworth, N R
Formato: Texto
Lenguaje:English
Publicado: 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240543/
https://www.ncbi.nlm.nih.gov/pubmed/11250806
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author Fabricant, D S
Farnsworth, N R
author_facet Fabricant, D S
Farnsworth, N R
author_sort Fabricant, D S
collection PubMed
description In this review we describe and discuss several approaches to selecting higher plants as candidates for drug development with the greatest possibility of success. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discovery purposes. We have identified 122 compounds of defined structure, obtained from only 94 species of plants, that are used globally as drugs and demonstrate that 80% of these have had an ethnomedical use identical or related to the current use of the active elements of the plant. We identify and discuss advantages and disadvantages of using plants as starting points for drug development, specifically those used in traditional medicine.
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spelling pubmed-12405432005-11-08 The value of plants used in traditional medicine for drug discovery. Fabricant, D S Farnsworth, N R Environ Health Perspect Research Article In this review we describe and discuss several approaches to selecting higher plants as candidates for drug development with the greatest possibility of success. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discovery purposes. We have identified 122 compounds of defined structure, obtained from only 94 species of plants, that are used globally as drugs and demonstrate that 80% of these have had an ethnomedical use identical or related to the current use of the active elements of the plant. We identify and discuss advantages and disadvantages of using plants as starting points for drug development, specifically those used in traditional medicine. 2001-03 /pmc/articles/PMC1240543/ /pubmed/11250806 Text en
spellingShingle Research Article
Fabricant, D S
Farnsworth, N R
The value of plants used in traditional medicine for drug discovery.
title The value of plants used in traditional medicine for drug discovery.
title_full The value of plants used in traditional medicine for drug discovery.
title_fullStr The value of plants used in traditional medicine for drug discovery.
title_full_unstemmed The value of plants used in traditional medicine for drug discovery.
title_short The value of plants used in traditional medicine for drug discovery.
title_sort value of plants used in traditional medicine for drug discovery.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240543/
https://www.ncbi.nlm.nih.gov/pubmed/11250806
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