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Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland.

A variety of human symptoms have been associated with exposure to the dinoflagellate Pfiesteria and have been grouped together into a syndrome termed "possible estuary-associated syndrome." Prospective cohort studies of health effects associated with exposure to estuarine waters that may c...

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Autores principales: Moe, C L, Turf, E, Oldach, D, Bell, P, Hutton, S, Savitz, D, Koltai, D, Turf, M, Ingsrisawang, L, Hart, R, Ball, J D, Stutts, M, McCarter, R, Wilson, L, Haselow, D, Grattan, L, Morris, J G, Weber, D J
Formato: Texto
Lenguaje:English
Publicado: 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240611/
https://www.ncbi.nlm.nih.gov/pubmed/11677189
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author Moe, C L
Turf, E
Oldach, D
Bell, P
Hutton, S
Savitz, D
Koltai, D
Turf, M
Ingsrisawang, L
Hart, R
Ball, J D
Stutts, M
McCarter, R
Wilson, L
Haselow, D
Grattan, L
Morris, J G
Weber, D J
author_facet Moe, C L
Turf, E
Oldach, D
Bell, P
Hutton, S
Savitz, D
Koltai, D
Turf, M
Ingsrisawang, L
Hart, R
Ball, J D
Stutts, M
McCarter, R
Wilson, L
Haselow, D
Grattan, L
Morris, J G
Weber, D J
author_sort Moe, C L
collection PubMed
description A variety of human symptoms have been associated with exposure to the dinoflagellate Pfiesteria and have been grouped together into a syndrome termed "possible estuary-associated syndrome." Prospective cohort studies of health effects associated with exposure to estuarine waters that may contain Pfiesteria spp. and related organisms are in progress in North Carolina, Virginia, and Maryland. The three studies recruited cohorts of 118-238 subjects who work or engaged in recreation in estuary waters. Baseline health and neuropsychological evaluations are conducted, and study subjects are followed prospectively for 2-5 years with periodic assessments of health and performance on a battery of neuropsychological tests. Health symptoms and estuary water exposure are recorded by telephone interviews or diaries every 1-2 weeks. Water quality information, including measurements of Pfiesteria spp., is collected in the areas where the subjects are working. Because it is not possible to measure individual exposure to Pfiesteria or a toxin produced by this organism, these studies examine surrogate exposure measures (e.g., time spent in estuary waters, in a fish kill area, or in waters where Pfiesteria DNA was detected by molecular amplification). Preliminary analyses of the first 2 years (1998-2000) of data indicate that none of the three ongoing cohorts have detected adverse health effects. However, there have not been any reported fish kills associated with Pfiesteria since the studies began, so it is possible that none of the study subjects have been exposed to toxin-producing Pfiesteria spp.
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spelling pubmed-12406112005-11-08 Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland. Moe, C L Turf, E Oldach, D Bell, P Hutton, S Savitz, D Koltai, D Turf, M Ingsrisawang, L Hart, R Ball, J D Stutts, M McCarter, R Wilson, L Haselow, D Grattan, L Morris, J G Weber, D J Environ Health Perspect Research Article A variety of human symptoms have been associated with exposure to the dinoflagellate Pfiesteria and have been grouped together into a syndrome termed "possible estuary-associated syndrome." Prospective cohort studies of health effects associated with exposure to estuarine waters that may contain Pfiesteria spp. and related organisms are in progress in North Carolina, Virginia, and Maryland. The three studies recruited cohorts of 118-238 subjects who work or engaged in recreation in estuary waters. Baseline health and neuropsychological evaluations are conducted, and study subjects are followed prospectively for 2-5 years with periodic assessments of health and performance on a battery of neuropsychological tests. Health symptoms and estuary water exposure are recorded by telephone interviews or diaries every 1-2 weeks. Water quality information, including measurements of Pfiesteria spp., is collected in the areas where the subjects are working. Because it is not possible to measure individual exposure to Pfiesteria or a toxin produced by this organism, these studies examine surrogate exposure measures (e.g., time spent in estuary waters, in a fish kill area, or in waters where Pfiesteria DNA was detected by molecular amplification). Preliminary analyses of the first 2 years (1998-2000) of data indicate that none of the three ongoing cohorts have detected adverse health effects. However, there have not been any reported fish kills associated with Pfiesteria since the studies began, so it is possible that none of the study subjects have been exposed to toxin-producing Pfiesteria spp. 2001-10 /pmc/articles/PMC1240611/ /pubmed/11677189 Text en
spellingShingle Research Article
Moe, C L
Turf, E
Oldach, D
Bell, P
Hutton, S
Savitz, D
Koltai, D
Turf, M
Ingsrisawang, L
Hart, R
Ball, J D
Stutts, M
McCarter, R
Wilson, L
Haselow, D
Grattan, L
Morris, J G
Weber, D J
Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland.
title Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland.
title_full Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland.
title_fullStr Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland.
title_full_unstemmed Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland.
title_short Cohort studies of health effects among people exposed to estuarine waters: North Carolina, Virginia, and Maryland.
title_sort cohort studies of health effects among people exposed to estuarine waters: north carolina, virginia, and maryland.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240611/
https://www.ncbi.nlm.nih.gov/pubmed/11677189
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