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Irreversible binding and adrenocorticolytic activity of the DDT metabolite 3-methylsulfonyl-DDE examined in tissue-slice culture.

The persistent adrenocorticolytic DDT metabolite 3-methylsulfonyl-DDE (MeSO(2)-DDE) was originally identified in Baltic grey seals, a population suffering from adrenocortical hyperplasia. In mice, MeSO(2)-DDE induces mitochondrial degeneration and cellular necrosis in the adrenal zona fasciculata. I...

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Detalles Bibliográficos
Autores principales:	Lindhe , O, Lund, B O, Bergman , A, Brandt, I
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Science 2001
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240628/ https://www.ncbi.nlm.nih.gov/pubmed/11266318

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