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In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane.
In this study, we integrated our understanding of biochemistry, physiology, and metabolism of three commonly used organic solvents with computer simulation to present a new approach that we call "in silico" toxicology. Thus, we developed an interactive physiologically based pharmacokinetic...
Autores principales: | Dobrev, Ivan D, Andersen, Melvin E, Yang, Raymond S H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241030/ https://www.ncbi.nlm.nih.gov/pubmed/12361929 |
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