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Molecular mechanisms in nickel carcinogenesis: modeling Ni(II) binding site in histone H4.

Ni(II) compounds are well known as human carcinogens, though the molecular events which are responsible for this are not yet fully understood. It has been proposed that the binding of N(II) ions within the cell nucleus is a crucial element in the mechanism of carcinogenesis. The most abundant protei...

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Detalles Bibliográficos
Autores principales: Zoroddu, Maria Antonietta, Schinocca, Laura, Kowalik-Jankowska, Teresa, Kozlowski, Henryk, Salnikow, Konstantin, Costa, Max
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241232/
https://www.ncbi.nlm.nih.gov/pubmed/12426119