Chromate-induced epimutations in mammalian cells.

Epigenetic gene silencing by aberrant DNA methylation of gene promoter regions is a nonmutagenic but heritable epigenetic mechanism that may mistakenly cause the silencing of important cancer-related tumor suppressor genes. Using a transgenic, V79-derived, mammalian cell line (G12) that contains a b...

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Detalles Bibliográficos
Autores principales: Klein, Catherine B, Su, Lin, Bowser, Darlene, Leszczynska, Joanna
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241236/
https://www.ncbi.nlm.nih.gov/pubmed/12426123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241236/
https://www.ncbi.nlm.nih.gov/pubmed/12426123

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