Inhalation exposure of rats to asphalt fumes generated at paving temperatures alters pulmonary xenobiotic metabolism pathways without lung injury.

Asphalt fumes are complex mixtures of various organic compounds, including polycyclic aromatic hydrocarbons (PAHs). PAHs require bioactivation by the cytochrome P-450 monooxygenase system to exert toxic/carcinogenic effects. The present study was carried out to characterize the acute pulmonary infla...

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Detalles Bibliográficos
Autores principales: Ma, Jane Y C, Rengasamy, Apavoo, Frazer, Dave, Barger, Mark W, Hubbs, Ann F, Battelli, Lori, Tomblyn, Seith, Stone, Samuel, Castranova, Vince
Formato: Texto
Lenguaje:English
Publicado: 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241577/
https://www.ncbi.nlm.nih.gov/pubmed/12842776

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