Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances.

This article is a review of the use, by regulatory agencies and authorities, of quantitative structure-activity relationships (QSARs) to predict ecologic effects and environmental fate of chemicals. For many years, the U.S. Environmental Protection Agency has been the most prominent regulatory agenc...

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Detalles Bibliográficos
Autores principales: Cronin, Mark T D, Walker, John D, Jaworska, Joanna S, Comber, Michael H I, Watts, Christopher D, Worth, Andrew P
Formato: Texto
Lenguaje:English
Publicado: 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241621/
https://www.ncbi.nlm.nih.gov/pubmed/12896861
Descripción
Sumario:This article is a review of the use, by regulatory agencies and authorities, of quantitative structure-activity relationships (QSARs) to predict ecologic effects and environmental fate of chemicals. For many years, the U.S. Environmental Protection Agency has been the most prominent regulatory agency using QSARs to predict the ecologic effects and environmental fate of chemicals. However, as increasing numbers of standard QSAR methods are developed and validated to predict ecologic effects and environmental fate of chemicals, it is anticipated that more regulatory agencies and authorities will find them to be acceptable alternatives to chemical testing.

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