Cargando…
Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances.
This article is a review of the use, by regulatory agencies and authorities, of quantitative structure-activity relationships (QSARs) to predict ecologic effects and environmental fate of chemicals. For many years, the U.S. Environmental Protection Agency has been the most prominent regulatory agenc...
Autores principales: | , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241621/ https://www.ncbi.nlm.nih.gov/pubmed/12896861 |
_version_ | 1782125458118148096 |
---|---|
author | Cronin, Mark T D Walker, John D Jaworska, Joanna S Comber, Michael H I Watts, Christopher D Worth, Andrew P |
author_facet | Cronin, Mark T D Walker, John D Jaworska, Joanna S Comber, Michael H I Watts, Christopher D Worth, Andrew P |
author_sort | Cronin, Mark T D |
collection | PubMed |
description | This article is a review of the use, by regulatory agencies and authorities, of quantitative structure-activity relationships (QSARs) to predict ecologic effects and environmental fate of chemicals. For many years, the U.S. Environmental Protection Agency has been the most prominent regulatory agency using QSARs to predict the ecologic effects and environmental fate of chemicals. However, as increasing numbers of standard QSAR methods are developed and validated to predict ecologic effects and environmental fate of chemicals, it is anticipated that more regulatory agencies and authorities will find them to be acceptable alternatives to chemical testing. |
format | Text |
id | pubmed-1241621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
record_format | MEDLINE/PubMed |
spelling | pubmed-12416212005-11-08 Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. Cronin, Mark T D Walker, John D Jaworska, Joanna S Comber, Michael H I Watts, Christopher D Worth, Andrew P Environ Health Perspect Research Article This article is a review of the use, by regulatory agencies and authorities, of quantitative structure-activity relationships (QSARs) to predict ecologic effects and environmental fate of chemicals. For many years, the U.S. Environmental Protection Agency has been the most prominent regulatory agency using QSARs to predict the ecologic effects and environmental fate of chemicals. However, as increasing numbers of standard QSAR methods are developed and validated to predict ecologic effects and environmental fate of chemicals, it is anticipated that more regulatory agencies and authorities will find them to be acceptable alternatives to chemical testing. 2003-08 /pmc/articles/PMC1241621/ /pubmed/12896861 Text en |
spellingShingle | Research Article Cronin, Mark T D Walker, John D Jaworska, Joanna S Comber, Michael H I Watts, Christopher D Worth, Andrew P Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. |
title | Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. |
title_full | Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. |
title_fullStr | Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. |
title_full_unstemmed | Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. |
title_short | Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. |
title_sort | use of qsars in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241621/ https://www.ncbi.nlm.nih.gov/pubmed/12896861 |
work_keys_str_mv | AT croninmarktd useofqsarsininternationaldecisionmakingframeworkstopredictecologiceffectsandenvironmentalfateofchemicalsubstances AT walkerjohnd useofqsarsininternationaldecisionmakingframeworkstopredictecologiceffectsandenvironmentalfateofchemicalsubstances AT jaworskajoannas useofqsarsininternationaldecisionmakingframeworkstopredictecologiceffectsandenvironmentalfateofchemicalsubstances AT combermichaelhi useofqsarsininternationaldecisionmakingframeworkstopredictecologiceffectsandenvironmentalfateofchemicalsubstances AT wattschristopherd useofqsarsininternationaldecisionmakingframeworkstopredictecologiceffectsandenvironmentalfateofchemicalsubstances AT worthandrewp useofqsarsininternationaldecisionmakingframeworkstopredictecologiceffectsandenvironmentalfateofchemicalsubstances |