Prime–boost vaccination with plasmid and adenovirus gene vaccines control HER2/neu(+ )metastatic breast cancer in mice

INTRODUCTION: Once metastasis has occurred, the possibility of completely curing breast cancer is unlikely, particularly for the 30 to 40% of cancers overexpressing the gene for HER2/neu. A vaccine targeting p185, the protein product of the HER2/neu gene, could have therapeutic application by contro...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Wang, Jian-Ping, Rao, Xiao-Mei, Price, Janet E, Zhou, Heshan S, Lachman, Lawrence B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242122/
https://www.ncbi.nlm.nih.gov/pubmed/16168101
http://dx.doi.org/10.1186/bcr1199

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