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Somatic mutation and gain of copy number of PIK3CA in human breast cancer

INTRODUCTION: Phosphatidylinositol 3-kinases (PI3Ks) are a group of lipid kinases that regulate signaling pathways involved in cell proliferation, adhesion, survival, and motility. Even though PIK3CA amplification and somatic mutation have been reported previously in various kinds of human cancers,...

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Detalles Bibliográficos
Autores principales:	Wu, Guojun, Xing, Mingzhao, Mambo, Elizabeth, Huang, Xin, Liu, Junwei, Guo, Zhongmin, Chatterjee, Aditi, Goldenberg, David, Gollin, Susanne M, Sukumar, Saraswati, Trink, Barry, Sidransky, David
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242128/ https://www.ncbi.nlm.nih.gov/pubmed/16168105 http://dx.doi.org/10.1186/bcr1262

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