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Early stopping of clinical trials

Early stopping of clinical trials in favour of a new treatment creates ethical and scientific difficulties, which are different from those associated with early stopping due to toxicity or futility. Two major breast cancer trials have recently taken such a decision, and the problem is relevant for s...

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Detalles Bibliográficos
Autores principales: Cuzick, Jack, Howell, Anthony, Forbes, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242138/
https://www.ncbi.nlm.nih.gov/pubmed/16168134
http://dx.doi.org/10.1186/bcr1280