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Genotypes and haplotypes of the methyl-CpG-binding domain 2 modify breast cancer risk dependent upon menopausal status

INTRODUCTION: MBD2, the gene encoding methyl-CpG-binding domain (MBD)2, is a major methylation related gene and functions as a transcriptional repressor that can specifically bind to the methylated regions of other genes. MBD2 may also mediate gene activation because of its potential DNA demethylase...

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Detalles Bibliográficos
Autores principales: Zhu, Yong, Brown, Heather N, Zhang, Yawei, Holford, Theodore R, Zheng, Tongzhang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242141/
https://www.ncbi.nlm.nih.gov/pubmed/16168120
http://dx.doi.org/10.1186/bcr1283