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Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment

INTRODUCTION: Polyamines affect proliferation, differentiation, migration and apoptosis of cells, indicating their potential as a target for cancer chemotherapy. Ornithine decarboxylase converts ornithine to putrescine and is the rate-limiting step in polyamine synthesis. α-Difluoromethylornithine (...

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Detalles Bibliográficos
Autores principales:	Richert, Monica M, Phadke, Pushkar A, Matters, Gail, DiGirolamo, Douglas J, Washington, Sharlene, Demers, Laurence M, Bond, Judith S, Manni, Andrea, Welch, Danny R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242150/ https://www.ncbi.nlm.nih.gov/pubmed/16168128 http://dx.doi.org/10.1186/bcr1292

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