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Expression of hypoxia-inducible factor 1 alpha and its downstream targets in fibroepithelial tumors of the breast

INTRODUCTION: Hypoxia-inducible factor 1 (HIF-1) alpha and its downstream targets carbonic anhydrase IX (CAIX) and vascular endothelial growth factor (VEGF) are key factors in the survival of proliferating tumor cells in a hypoxic microenvironment. We studied the expression and prognostic relevance...

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Detalles Bibliográficos
Autores principales: Kuijper, Arno, van der Groep, Petra, van der Wall, Elsken, van Diest, Paul J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242154/
https://www.ncbi.nlm.nih.gov/pubmed/16168127
http://dx.doi.org/10.1186/bcr1296