Canonical Wnt signaling: high-throughput RNAi widens the path

The canonical Wnt signaling pathway is highly conserved in evolution, widely used throughout animal development, and frequently hyperactive in cancer. Although Wnt signaling has been the subject of extensive genetic analysis in the past, some 200 genes have now been identified as candidate modulator...

Descripción completa

Detalles Bibliográficos
Autor principal: Brown, Anthony MC
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242201/
https://www.ncbi.nlm.nih.gov/pubmed/16168092
http://dx.doi.org/10.1186/gb-2005-6-9-231
_version_ 1782125610885185536
author Brown, Anthony MC
author_facet Brown, Anthony MC
author_sort Brown, Anthony MC
collection PubMed
description The canonical Wnt signaling pathway is highly conserved in evolution, widely used throughout animal development, and frequently hyperactive in cancer. Although Wnt signaling has been the subject of extensive genetic analysis in the past, some 200 genes have now been identified as candidate modulators of this pathway by a recent study using high-throughput RNAi screening.
format Text
id pubmed-1242201
institution National Center for Biotechnology Information
language English
publishDate 2005
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-12422012005-10-06 Canonical Wnt signaling: high-throughput RNAi widens the path Brown, Anthony MC Genome Biol Minireview The canonical Wnt signaling pathway is highly conserved in evolution, widely used throughout animal development, and frequently hyperactive in cancer. Although Wnt signaling has been the subject of extensive genetic analysis in the past, some 200 genes have now been identified as candidate modulators of this pathway by a recent study using high-throughput RNAi screening. BioMed Central 2005 2005-08-31 /pmc/articles/PMC1242201/ /pubmed/16168092 http://dx.doi.org/10.1186/gb-2005-6-9-231 Text en Copyright © 2005 BioMed Central Ltd
spellingShingle Minireview
Brown, Anthony MC
Canonical Wnt signaling: high-throughput RNAi widens the path
title Canonical Wnt signaling: high-throughput RNAi widens the path
title_full Canonical Wnt signaling: high-throughput RNAi widens the path
title_fullStr Canonical Wnt signaling: high-throughput RNAi widens the path
title_full_unstemmed Canonical Wnt signaling: high-throughput RNAi widens the path
title_short Canonical Wnt signaling: high-throughput RNAi widens the path
title_sort canonical wnt signaling: high-throughput rnai widens the path
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242201/
https://www.ncbi.nlm.nih.gov/pubmed/16168092
http://dx.doi.org/10.1186/gb-2005-6-9-231
work_keys_str_mv AT brownanthonymc canonicalwntsignalinghighthroughputrnaiwidensthepath

Ejemplares similares