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Reciprocal role of cyclins and cyclin kinase inhibitor p21(WAF1/CIP1 )on lymphocyte proliferation, allo-immune activation and inflammation
BACKGROUND: Immune activation that results due to the aberrant proliferation of lymphocytes leads to inflammation and graft rejection in organ transplant recipients. We hypothesize that the cell cycle control and inflammation are parallel events, inhibition of cellular proliferation by cyclin kinase...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242230/ https://www.ncbi.nlm.nih.gov/pubmed/16176581 http://dx.doi.org/10.1186/1471-2172-6-22 |