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Neonatal local noxious insult affects gene expression in the spinal dorsal horn of adult rats
Neonatal noxious insult produces a long-term effect on pain processing in adults. Rats subjected to carrageenan (CAR) injection in one hindpaw within the sensitive period develop bilateral hypoalgesia as adults. In the same rats, inflammation of the hindpaw, which was the site of the neonatal injury...
Autores principales: | Ren, Ke, Novikova, Svetlana I, He, Fang, Dubner, Ronald, Lidow, Michael S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242251/ https://www.ncbi.nlm.nih.gov/pubmed/16179088 http://dx.doi.org/10.1186/1744-8069-1-27 |
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