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RLIP76, a non-ABC transporter, and drug resistance in epilepsy

BACKGROUND: Permeability of the blood-brain barrier is one of the factors determining the bioavailability of therapeutic drugs and resistance to chemically different antiepileptic drugs is a consequence of decreased intracerebral accumulation. The ABC transporters, particularly P-glycoprotein, are k...

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Detalles Bibliográficos
Autores principales: Awasthi, Sanjay, Hallene, Kerri L, Fazio, Vince, Singhal, Sharad S, Cucullo, Luca, Awasthi, Yogesh C, Dini, Gabriele, Janigro, Damir
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1249579/
https://www.ncbi.nlm.nih.gov/pubmed/16188027
http://dx.doi.org/10.1186/1471-2202-6-61