Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

The crystal structures of six complexes between aminoglycoside antibiotics (neamine, gentamicin C1A, kanamycin A, ribostamycin, lividomycin A and neomycin B) and oligonucleotides containing the decoding A site of bacterial ribosomes are reported at resolutions between 2.2 and 3.0 Å. Although the num...

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Detalles Bibliográficos
Autores principales: François, Boris, Russell, Rupert J. M., Murray, James B., Aboul-ela, Fareed, Masquida, Benoît, Vicens, Quentin, Westhof, Eric
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1251667/
https://www.ncbi.nlm.nih.gov/pubmed/16214802
http://dx.doi.org/10.1093/nar/gki862

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