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B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response
The influence of HLA DRB1 alleles on B-cell homeostasis was analyzed in 164 patients with rheumatoid arthritis (RA). The percentages of CD19(+) B lymphocytes determined in the peripheral circulation of 94 retrospectively recruited RA patients followed a bimodal distribution. Two frequency peaks (B-c...
Autores principales: | Wagner, Ulf, Kaltenhäuser, Sylke, Pierer, Matthias, Wilke, Bernd, Arnold, Sybille, Häntzschel, Holm |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC125293/ https://www.ncbi.nlm.nih.gov/pubmed/12106500 http://dx.doi.org/10.1186/ar420 |
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