Identification of unique reciprocal and non reciprocal cross packaging relationships between HIV-1, HIV-2 and SIV reveals an efficient SIV/HIV-2 lentiviral vector system with highly favourable features for in vivo testing and clinical usage

BACKGROUND: Lentiviral vectors have shown immense promise as vehicles for gene delivery to non-dividing cells particularly to cells of the central nervous system (CNS). Improvements in the biosafety of viral vectors are paramount as lentiviral vectors move into human clinical trials. This study inve...

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Detalles Bibliográficos
Autores principales: Strappe, Padraig M, Hampton, David W, Brown, Douglas, Cachon-Gonzalez, Begona, Caldwell, Maeve, Fawcett, James W, Lever, Andrew ML
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253535/
https://www.ncbi.nlm.nih.gov/pubmed/16168051
http://dx.doi.org/10.1186/1742-4690-2-55

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