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Squamous Cell Carcinoma of the Skin and Coal Tar Creosote Exposure in a Railroad Worker

A 50-year-old male railroad worker presented to his primary care physician with an erythematous, tender skin lesion on the right knee; a biopsy of this lesion revealed squamous cell carcinoma in situ. The site of the lesion was sun-protected but had been associated with 30 years of creosote-soaked c...

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Detalles Bibliográficos
Autores principales: Carlsten, Chris, Hunt, Stephen Carl, Kaufman, Joel D.
Formato: Texto
Lenguaje:English
Publicado: National Institue of Environmental Health Sciences 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253716/
https://www.ncbi.nlm.nih.gov/pubmed/15626654
http://dx.doi.org/10.1289/ehp.7373
Descripción
Sumario:A 50-year-old male railroad worker presented to his primary care physician with an erythematous, tender skin lesion on the right knee; a biopsy of this lesion revealed squamous cell carcinoma in situ. The site of the lesion was sun-protected but had been associated with 30 years of creosote-soaked clothing. In this article, we review dermal and other malignancies associated with creosote, along with creosote occupational exposures and exposure limits. This is a unique case, given the lack of other, potentially confounding, polyaromatic hydrocarbons and the sun-protected location of the lesion.