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Yersinia pseudotuberculosis Spatially Controls Activation and Misregulation of Host Cell Rac1

Yersinia pseudotuberculosis binds host cells and modulates the mammalian Rac1 guanosine triphosphatase (GTPase) at two levels. Activation of Rac1 results from integrin receptor engagement, while misregulation is promoted by translocation of YopE and YopT proteins into target cells. Little is known r...

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Detalles Bibliográficos
Autores principales: Wong, Ka-Wing, Isberg, Ralph R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253843/
https://www.ncbi.nlm.nih.gov/pubmed/16228016
http://dx.doi.org/10.1371/journal.ppat.0010016