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Global approaches to understanding ubiquitination

Ubiquitination - the linkage of one or more molecules of the protein ubiquitin to another protein - regulates a wide range of biological processes in all eukaryotes. We review the proteome-wide strategies that are being used to study aspects of ubiquitin biology, including substrates, components of...

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Detalles Bibliográficos
Autores principales: Kaiser, Peter, Huang, Lan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257457/
https://www.ncbi.nlm.nih.gov/pubmed/16207362
http://dx.doi.org/10.1186/gb-2005-6-10-233
Descripción
Sumario:Ubiquitination - the linkage of one or more molecules of the protein ubiquitin to another protein - regulates a wide range of biological processes in all eukaryotes. We review the proteome-wide strategies that are being used to study aspects of ubiquitin biology, including substrates, components of the proteasome and ubiquitin ligases, and deubiquitination.