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A protein folding potential that places the native states of a large number of proteins near a local minimum

BACKGROUND: We present a simple method to train a potential function for the protein folding problem which, even though trained using a small number of proteins, is able to place a significantly large number of native conformations near a local minimum. The training relies on generating decoys by en...

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Detalles Bibliográficos
Autores principales: Chhajer, Mukesh, Crippen, Gordon M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126205/
https://www.ncbi.nlm.nih.gov/pubmed/12165098
http://dx.doi.org/10.1186/1472-6807-2-4