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Native interface of the SAM domain polymer of TEL
BACKGROUND: TEL is a transcriptional repressor containing a SAM domain that forms a helical polymer. In a number of hematologic malignancies, chromosomal translocations lead to aberrant fusions of TEL-SAM to a variety of other proteins, including many tyrosine kinases. TEL-SAM polymerization results...
Autores principales: | Tran, Hoang H, Kim, Chongwoo A, Faham, Salem, Siddall, Marie-Claire, Bowie, James U |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126206/ https://www.ncbi.nlm.nih.gov/pubmed/12193272 http://dx.doi.org/10.1186/1472-6807-2-5 |
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