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Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis
BACKGROUND: NF1 refers to type 1 neurofibromatosis syndrome, which has been linked with mutations of the large NF1 gene. NF1 tumor suppressor protein, neurofibromin, has been shown to regulate ras: the NF1 protein contains a GTPase activating protein (GAP) related domain which functions as p21rasGAP...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126231/ https://www.ncbi.nlm.nih.gov/pubmed/12199909 http://dx.doi.org/10.1186/1471-5945-2-10 |