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Profound effect of normalization on detection of differentially expressed genes in oligonucleotide microarray data analysis
BACKGROUND: Oligonucleotide microarrays measure the relative transcript abundance of thousands of mRNAs in parallel. A large number of procedures for normalization and detection of differentially expressed genes have been proposed. However, the relative impact of these methods on the detection of di...
Autores principales: | Hoffmann, Reinhard, Seidl, Thomas, Dugas, Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126238/ https://www.ncbi.nlm.nih.gov/pubmed/12184807 |
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