Cargando…

PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol

BACKGROUND: A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific solutes, required specification of a large number of parameters and have not been designed for general...

Descripción completa

Detalles Bibliográficos
Autor principal:	Levitt, David G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126244/ https://www.ncbi.nlm.nih.gov/pubmed/12182760 http://dx.doi.org/10.1186/1472-6904-2-5

Ejemplares similares

PKQuest_Java: free, interactive physiologically based pharmacokinetic software package and tutorial
por: Levitt, David G
Publicado: (2009)

PKQuest: measurement of intestinal absorption and first pass metabolism – application to human ethanol pharmacokinetics
por: Levitt, David G
Publicado: (2002)

PKQuest: volatile solutes – application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics
por: Levitt, David G
Publicado: (2002)

PKQuest: capillary permeability limitation and plasma protein binding – application to human inulin, dicloxacillin and ceftriaxone pharmacokinetics
por: Levitt, David G
Publicado: (2002)

PKQuest: PBPK modeling of highly lipid soluble and extracellular solutes
por: Levitt, David G.
Publicado: (2018)

Human physiologically based pharmacokinetic model for propofol
por: Levitt, David G, et al.
Publicado: (2005)

Physiologically based pharmacokinetic modeling of arterial – antecubital vein concentration difference
por: Levitt, David G
Publicado: (2004)

The use of a physiologically based pharmacokinetic model to evaluate deconvolution measurements of systemic absorption
por: Levitt, David G
Publicado: (2003)

Human physiologically based pharmacokinetic model for ACE inhibitors: ramipril and ramiprilat
por: Levitt, David G, et al.
Publicado: (2006)

Development and Evaluation of a Physiologically Based Pharmacokinetic Drug-Disease Model of Propranolol for Suggesting Model Informed Dosing in Liver Cirrhosis Patients
por: Kalam, Muhammad Nasir, et al.
Publicado: (2021)

Pharmacokinetic Parameters and Over-Responsiveness of Iranian Population to Propranolol
por: Salehifar, Ebrahim, et al.
Publicado: (2017)

Application of Physiologically Based Pharmacokinetic Modeling to Predict Pharmacokinetics in Healthy Japanese Subjects
por: Matsumoto, Yuki, et al.
Publicado: (2018)

Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats
por: Asdaq, Syed Mohammed Basheeruddin, et al.
Publicado: (2011)

Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles
por: Carlander, Ulrika, et al.
Publicado: (2016)

Development and application of a simple pharmacokinetic model that quantitatively describes the distribution and elimination of the commonly measured proteins
por: Levitt, David G., et al.
Publicado: (2023)

Application of Physiologically Based Pharmacokinetic Modeling to Predict Acetaminophen Metabolism and Pharmacokinetics in Children
por: Jiang, X-L, et al.
Publicado: (2013)

Population Pharmacokinetics and Pharmacodynamics of Oral Propranolol in Pediatric Patients With Infantile Hemangioma
por: Takechi, Tomoki, et al.
Publicado: (2018)

Application of physiologically based pharmacokinetic modeling to predict the pharmacokinetics of telavancin in obesity with renal impairment
por: Wu, Wanhong, et al.
Publicado: (2021)

Application of Physiologically Based Pharmacokinetic Modeling to Predict Maternal Pharmacokinetics and Fetal Exposure to Oxcarbazepine
por: He, Lixia, et al.
Publicado: (2022)

Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment
por: Mumtaz, Moiz, et al.
Publicado: (2012)

Adapting physiologically-based pharmacokinetic models for machine learning applications
por: Habiballah, Sohaib, et al.
Publicado: (2023)

Applications of physiologic pharmacokinetic modeling in carcinogenic risk assessment.
por: Krewski, D, et al.
Publicado: (1994)

Increasing application of pediatric physiologically based pharmacokinetic models across academic and industry organizations
por: Johnson, Trevor N., et al.
Publicado: (2022)

Propranolol pharmacokinetics in infants treated for Infantile Hemangiomas requiring systemic therapy: Modeling and dosing regimen recommendations
por: Del Frari, Laurence, et al.
Publicado: (2018)

Physiologically Based Pharmacokinetic Modelling to Identify Physiological and Drug Parameters Driving Pharmacokinetics in Obese Individuals
por: Berton, Mattia, et al.
Publicado: (2022)

Application of physiologically based pharmacokinetic modeling for sertraline dosing recommendations in pregnancy
por: George, Blessy, et al.
Publicado: (2020)

Application of a physiologically based pharmacokinetic model to predict isoniazid disposition during pregnancy
por: Amaeze, Ogochukwu U., et al.
Publicado: (2023)

Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy
por: Colbers, Angela, et al.
Publicado: (2015)

Application of Physiologically Based Pharmacokinetic Modeling to Predict the Effect of Renal Impairment on the Pharmacokinetics of Olanzapine and Samidorphan Given in Combination
por: Sun, Lei, et al.
Publicado: (2020)

Quantitative modeling of the physiology of ascites in portal hypertension
por: Levitt, David G, et al.
Publicado: (2012)

Development and Application of a Physiologically Based Pharmacokinetic Model for Diclazuril in Broiler Chickens
por: Yang, Fang, et al.
Publicado: (2023)

Hybrid physiologically‐based pharmacokinetic model for remdesivir: Application to SARS‐CoV‐2
por: Gallo, James M.
Publicado: (2021)

Minimal physiologically‐based hybrid model of pharmacokinetics in pregnant women: Application to antenatal corticosteroids
por: Krzyzanski, Wojciech, et al.
Publicado: (2023)

The pharmacokinetics of the interstitial space in humans
por: Levitt, David G
Publicado: (2003)

Predicting Resolvin D1 Pharmacokinetics in Humans with Physiologically‐Based Pharmacokinetic Modeling
por: Yellepeddi, Venkata K., et al.
Publicado: (2020)

Effects of Lasmiditan on Cardiovascular Parameters and Pharmacokinetics in Healthy Subjects Receiving Oral Doses of Propranolol
por: Tsai, Max, et al.
Publicado: (2020)

Unraveling bisphenol A pharmacokinetics using physiologically based pharmacokinetic modeling
por: Yang, Xiaoxia, et al.
Publicado: (2015)

Physiologically‐based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate
por: Mahdy, Walaa Y. B., et al.
Publicado: (2023)

A Physiologically Based Pharmacokinetic Model for Predicting Diazepam Pharmacokinetics after Intravenous, Oral, Intranasal, and Rectal Applications
por: Khalid, Sundus, et al.
Publicado: (2021)

A survey on the application of oral propranolol and atenolol for the management of infantile hemangiomas in mainland China: Survey on propranolol atenolol hemangiomas
por: Zhao, Ze-Liang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rc83hn3pdv96c0oipj1jnul308