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Sex steroids do not affect shigatoxin cytotoxicity on human renal tubular or glomerular cells

BACKGROUND: The greater susceptibility of children to renal injury in post-diarrheal hemolytic-uremic syndrome (HUS) may be related, at least in part, to heightened renal cell sensitivity to the cytotoxic effect of Shiga toxin (Stx), the putative mediator of kidney damage in HUS. We hypothesized tha...

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Detalles Bibliográficos
Autores principales: Hughes, Alisa K, Schmid, Douglas I, Kohan, Donald E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126269/
https://www.ncbi.nlm.nih.gov/pubmed/12181081
http://dx.doi.org/10.1186/1471-2369-3-6

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