Probing stereoselective inhibition of the acyl binding site of cholesterol esterase with four diastereomers of 2'-N-α-methylbenzylcarbamyl-1, 1'-bi-2-naphthol

BACKGROUND: Recently there has been increased interest in pancreatic cholesterol esterase due to correlation between enzymatic activity in vivo and absorption of dietary cholesterol. Cholesterol esterase plays a role in digestive lipid absorption in the upper intestinal tract, though its role in cho...

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Detalles Bibliográficos
Autores principales: Chiou, Shyh-Ying, Lai, Cheng-Yue, Lin, Long-Yau, Lin, Gialih
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262691/
https://www.ncbi.nlm.nih.gov/pubmed/16176589
http://dx.doi.org/10.1186/1471-2091-6-17

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