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Identification of disease causing loci using an array-based genotyping approach on pooled DNA
BACKGROUND: Pooling genomic DNA samples within clinical classes of disease followed by genotyping on whole-genome SNP microarrays, allows for rapid and inexpensive genome-wide association studies. Key to the success of these studies is the accuracy of the allelic frequency calculations, the ability...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262713/ https://www.ncbi.nlm.nih.gov/pubmed/16197552 http://dx.doi.org/10.1186/1471-2164-6-138 |