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T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory

BACKGROUND: Single Nucleotide Polymorphism (SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produces large amounts of data that are difficult to process by hand. Laboratories not equipped with a Laboratory Information...

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Detalles Bibliográficos
Autores principales: Monnier, Stéphanie, Cox, David G, Albion, Tim, Canzian, Federico
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266351/
https://www.ncbi.nlm.nih.gov/pubmed/16221298
http://dx.doi.org/10.1186/1471-2105-6-246
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author Monnier, Stéphanie
Cox, David G
Albion, Tim
Canzian, Federico
author_facet Monnier, Stéphanie
Cox, David G
Albion, Tim
Canzian, Federico
author_sort Monnier, Stéphanie
collection PubMed
description BACKGROUND: Single Nucleotide Polymorphism (SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produces large amounts of data that are difficult to process by hand. Laboratories not equipped with a Laboratory Information Management System (LIMS) need tools to organize the data flow. RESULTS: We propose a package of Visual Basic programs focused on sample management and on the parsing of input and output TaqMan files. The code is written in Visual Basic, embedded in the Microsoft Office package, and it allows anyone to have access to those tools, without any programming skills and with basic computer requirements. CONCLUSION: We have created useful tools focused on management of TaqMan genotyping data, a critical issue in genotyping laboratories whithout a more sophisticated and expensive system, such as a LIMS.
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spelling pubmed-12663512005-10-27 T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory Monnier, Stéphanie Cox, David G Albion, Tim Canzian, Federico BMC Bioinformatics Software BACKGROUND: Single Nucleotide Polymorphism (SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produces large amounts of data that are difficult to process by hand. Laboratories not equipped with a Laboratory Information Management System (LIMS) need tools to organize the data flow. RESULTS: We propose a package of Visual Basic programs focused on sample management and on the parsing of input and output TaqMan files. The code is written in Visual Basic, embedded in the Microsoft Office package, and it allows anyone to have access to those tools, without any programming skills and with basic computer requirements. CONCLUSION: We have created useful tools focused on management of TaqMan genotyping data, a critical issue in genotyping laboratories whithout a more sophisticated and expensive system, such as a LIMS. BioMed Central 2005-10-12 /pmc/articles/PMC1266351/ /pubmed/16221298 http://dx.doi.org/10.1186/1471-2105-6-246 Text en Copyright © 2005 Monnier et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software
Monnier, Stéphanie
Cox, David G
Albion, Tim
Canzian, Federico
T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
title T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
title_full T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
title_fullStr T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
title_full_unstemmed T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
title_short T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
title_sort t.i.m.s: taqman information management system, tools to organize data flow in a genotyping laboratory
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266351/
https://www.ncbi.nlm.nih.gov/pubmed/16221298
http://dx.doi.org/10.1186/1471-2105-6-246
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