Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation

BACKGROUND: Interaction with integrin and focal adhesion kinase (FAK) regulates the cancer cell adhesion and invasion into extracellular matrix (ECM). In addition, phosphorylation of FAK correlates with the increase of cell motility and invasion. Adhesion and spreading of cancer cells on a variety o...

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Detalles Bibliográficos
Autores principales: Sawai, Hirozumi, Okada, Yuji, Funahashi, Hitoshi, Matsuo, Yoichi, Takahashi, Hiroki, Takeyama, Hiromitsu, Manabe, Tadao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266395/
https://www.ncbi.nlm.nih.gov/pubmed/16209712
http://dx.doi.org/10.1186/1476-4598-4-37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266395/
https://www.ncbi.nlm.nih.gov/pubmed/16209712
http://dx.doi.org/10.1186/1476-4598-4-37

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