Cargando…

Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation

BACKGROUND: Interaction with integrin and focal adhesion kinase (FAK) regulates the cancer cell adhesion and invasion into extracellular matrix (ECM). In addition, phosphorylation of FAK correlates with the increase of cell motility and invasion. Adhesion and spreading of cancer cells on a variety o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sawai, Hirozumi, Okada, Yuji, Funahashi, Hitoshi, Matsuo, Yoichi, Takahashi, Hiroki, Takeyama, Hiromitsu, Manabe, Tadao
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266395/ https://www.ncbi.nlm.nih.gov/pubmed/16209712 http://dx.doi.org/10.1186/1476-4598-4-37

Ejemplares similares

Interleukin-1α enhances the aggressive behavior of pancreatic cancer cells by regulating the α(6)β(1)-integrin and urokinase plasminogen activator receptor expression
por: Sawai, Hirozumi, et al.
Publicado: (2006)

Reactive Lymphoid Hyperplasia of the liver in a patient with colon cancer: report of two cases
por: Takahashi, Hiroki, et al.
Publicado: (2006)

The stem cell factor/c-kit receptor pathway enhances proliferation and invasion of pancreatic cancer cells
por: Yasuda, Akira, et al.
Publicado: (2006)

Successful paclitaxel-based chemotherapy for an alpha-fetoprotein-producing gastric cancer patient with multiple liver metastases
por: Takeyama, Hiromitsu, et al.
Publicado: (2007)

Solid variant of serous cystadenoma of the pancreas
por: Yasuda, Akira, et al.
Publicado: (2011)

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics
por: Schober, Markus, et al.
Publicado: (2007)

The KDEL receptor signalling cascade targets focal adhesion kinase on focal adhesions and invadopodia
por: Ruggiero, Carmen, et al.
Publicado: (2017)

Focal Adhesion Kinase Mediates the Integrin Signaling Requirement for Growth Factor Activation of Map Kinase
por: Renshaw, Mark W., et al.
Publicado: (1999)

Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival
por: Sawai, Hirozumi, et al.
Publicado: (2008)

Focal Adhesion Kinases in Adhesion Structures and Disease
por: Eleniste, Pierre P., et al.
Publicado: (2012)

Activation of Rho-kinase and focal adhesion kinase regulates the organization of stress fibers and focal adhesions in the central part of fibroblasts
por: Katoh, Kazuo
Publicado: (2017)

Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase
por: Banning, Antje, et al.
Publicado: (2018)

Activation of focal adhesion kinase enhances the adhesion of Fusarium solani to human corneal epithelial cells via the tyrosine-specific protein kinase signaling pathway
por: Pan, Xiaojing, et al.
Publicado: (2011)

Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling
por: Weng, Yun, et al.
Publicado: (2020)

Carbohydrate-Induced Insulin Signaling Activates Focal Adhesion Kinase: A Nutrient and Mechanotransduction Crossroads
por: Wilburn, Dylan T., et al.
Publicado: (2020)

Extracellular Matrix Survival Signals Transduced by Focal Adhesion Kinase Suppress p53-mediated Apoptosis
por: Ilić, Duško, et al.
Publicado: (1998)

Y‐27632, an Inhibitor of Rho‐associated Protein Kinase, Suppresses Tumor Cell Invasion via Regulation of Focal Adhesion and Focal Adhesion Kinase
por: Imamura, Fumio, et al.
Publicado: (2000)

Canstatin inhibits hypoxia-induced apoptosis through activation of integrin/focal adhesion kinase/Akt signaling pathway in H9c2 cardiomyoblasts
por: Kanazawa, Hiroki, et al.
Publicado: (2017)

Mechanism of Focal Adhesion Kinase Mechanosensing
por: Zhou, Jing, et al.
Publicado: (2015)

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin
por: Rondas, Dieter, et al.
Publicado: (2011)

Control of adhesion-dependent cell survival by focal adhesion kinase
Publicado: (1996)

Focal Adhesion Kinase Inhibitor Inhibits the Oxidative Damage Induced by Central Venous Catheter via Abolishing Focal Adhesion Kinase-Protein Kinase B Pathway Activation
por: Wang, Yanru, et al.
Publicado: (2021)

SAT-604 The Role of the Focal Adhesion Kinase Family in Leptin Receptor Signaling
por: Hadley, Colleen, et al.
Publicado: (2020)

MG53 inhibits angiogenesis through regulating focal adhesion kinase signalling
por: Dong, Jinling, et al.
Publicado: (2021)

Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation
por: Rodriguez, Uylissa A., et al.
Publicado: (2022)

The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma
por: Begum, Asma, et al.
Publicado: (2017)

Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration
por: Wu, Jui-Chung, et al.
Publicado: (2015)

ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain
por: Rashmi,, et al.
Publicado: (2021)

Focal adhesion kinase (FAK) expression and activation during lens development
por: Kokkinos, Maria I., et al.
Publicado: (2007)

Regulation of the Cell Cycle by Focal Adhesion Kinase
por: Zhao, Ji-He, et al.
Publicado: (1998)

Requirement of focal adhesion kinase in branching tubulogenesis
por: Wei, Wei-Chun, et al.
Publicado: (2009)

Emerging Roles of Focal Adhesion Kinase in Cancer
por: Tai, Yu-Ling, et al.
Publicado: (2015)

Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis
por: CAO, TING, et al.
Publicado: (2014)

Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKCβ and focal adhesion kinase
por: Shaheen, Samina, et al.
Publicado: (2017)

Focal Adhesion Kinase Fine Tunes Multifaced Signals toward Breast Cancer Progression
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2021)

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase
por: Owen, Katherine A., et al.
Publicado: (2007)

Integrin-Linked Kinase: A Multi-functional Regulator Modulating Extracellular Pressure-Stimulated Cancer Cell Adhesion through Focal Adhesion Kinase and AKT
por: Wang, Shouye, et al.
Publicado: (2009)

Thrombomodulin promotes focal adhesion kinase activation and contributes to angiogenesis by binding to fibronectin
por: Hsu, Yun-Yan, et al.
Publicado: (2016)

Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis
por: Zhao, Xue-Ke, et al.
Publicado: (2017)

Kisspeptin-10 increases collagen content in the myocardium by focal adhesion kinase activity
por: Radwańska, Paulina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nlh5b0obkr9qn5boumfmafv950