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Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene
Exon 3 of the human apolipoprotein A-II (apoA-II) gene is efficiently included in the mRNA although its acceptor site is significantly weak because of a peculiar (GU)(16) tract instead of a canonical polypyrimidine tract within the intron 2/exon 3 junction. Our previous studies demonstrated that the...
Autores principales: | Mercado, Pablo Arrisi, Ayala, Youhna M., Romano, Maurizio, Buratti, Emanuele, Baralle, Francisco E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270946/ https://www.ncbi.nlm.nih.gov/pubmed/16254078 http://dx.doi.org/10.1093/nar/gki897 |
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